Research & Publications

Advancing medicine through evidence-based research

Peer-reviewed publications, clinical trials, and case studies from HUKM specialists — freely accessible to the medical community.

Showing 12 of 12 publications
CardiologyClinical Trial2026·32 citations

AI-Assisted Early Detection of Ischemic Heart Disease in Southeast Asian Populations

Dr. Aisha Rahman, Dr. Rahim Yusof, Prof. K. Lim · Malaysian Journal of Cardiology

A prospective cohort study of 2,412 patients evaluating a deep-learning ECG classifier against consultant cardiologists for early ischemic detection. The model achieved AUC 0.94, outperforming standard triage in the ≥45 age group by 11%.

#AI#ECG#cardiology#screening
OncologyOriginal Research2025·21 citations

Immunotherapy Response Patterns in Nasopharyngeal Carcinoma: A 5-Year Retrospective

Dr. Priya Menon, Dr. Leong Mei Ling · Asia-Pacific Oncology Review

Retrospective analysis of 486 NPC patients treated with checkpoint inhibitors between 2020–2025. Median PFS improved from 8.2 to 14.6 months versus historic chemotherapy controls.

#oncology#immunotherapy#NPC
NeurologyClinical Trial2025·18 citations

Post-Stroke Rehabilitation Outcomes with VR-Guided Motor Therapy

Dr. Vincent Lee, Dr. Shanti Devi · Journal of Neurorehabilitation

Randomised controlled trial (n=180) comparing conventional physiotherapy versus VR-guided motor rehabilitation. VR arm showed 27% greater Fugl-Meyer improvement at 12 weeks.

#neurology#stroke#rehabilitation#VR
OrthopedicsCase Study2025·14 citations

Robotic-Assisted Total Knee Arthroplasty: HUKM Single-Centre Experience

Dr. Harris Mansor, Dr. Chen Wei Ming · Southeast Asian Journal of Orthopedic Surgery

Case series of 214 robotic-assisted TKAs. Component alignment within 2° in 96% of cases; 30-day readmission 2.3% vs national benchmark 4.8%.

#orthopedics#robotic surgery#arthroplasty
OBGYNOriginal Research2025·9 citations

Gestational Diabetes Screening Compliance in Klang Valley: A Community Study

Dr. Noraini Hassan, Dr. Joanne Koh · MJOG

Cross-sectional study of 1,240 pregnancies. Screening compliance rose from 62% to 88% after community nurse outreach, correlating with 34% fewer macrosomic births.

#OBGYN#gestational diabetes#public health
PediatricsClinical Trial2025·12 citations

Chatbot-Led Triage in Pediatric Emergency: Safety & Accuracy

Dr. Michael Wong, Dr. Nurul Huda · Pediatric Digital Health

Prospective evaluation of an LLM-based triage chatbot across 3,180 pediatric ED encounters. Concordance with senior triage nurses 92%; no missed high-acuity cases.

#pediatrics#AI#triage#chatbot
Health Services ResearchMeta-Analysis2024·27 citations

Health Tourism Demand Modelling for Malaysian Tertiary Hospitals

Dr. Haslina Bakar, Prof. A. Ismail · Health Policy Asia

Meta-analysis of 42 studies covering 2015–2024. Indonesian and Bangladeshi inbound patient volume forecast to grow 34% YoY through 2028.

#health tourism#economics#modelling
Digital HealthOriginal Research2024·16 citations

Multilingual Symptom Reporting Accuracy in Clinical Chatbots

Dr. Nurul Huda, Prof. T. Rajan · JAMIA Open

Comparative study of symptom recall accuracy across Bahasa Malaysia, English, Mandarin, Tamil and Arabic inputs. Accuracy delta closed to <3% with fine-tuned models.

#NLP#chatbot#multilingual#safety
Critical CareOriginal Research2024·19 citations

Predictive Modelling of ICU Bed Demand During Seasonal Respiratory Surges

Dr. Rahim Yusof, Dr. Haslina Bakar · Critical Care Analytics

Gradient-boosted model forecasting ICU occupancy 14 days ahead. MAPE 7.4% during 2023 flu season, enabling proactive staffing and reducing overflow by 22%.

#ICU#forecasting#capacity
CardiologyReview2024·11 citations

Patient-Reported Outcomes After Cardiac Rehabilitation: A Longitudinal Registry

Dr. Aisha Rahman, Nur Farah Aziz · Cardiology Registry Review

Two-year registry of 612 post-MI patients. 78% achieved target functional capacity; adherence to Mediterranean-style diet was the strongest predictor of PROM improvement.

#cardiology#PROMs#rehabilitation
Digital HealthOriginal Research2024·8 citations

Telemedicine Adoption Among Elderly Malaysians: Barriers and Enablers

Dr. Joanne Koh, Sarah Lim · Digital Health Malaysia

Mixed-methods study of 420 participants aged 60+. Language and interface simplicity were the top adoption drivers; smartphone literacy programmes lifted uptake 41%.

#telemedicine#elderly#adoption
Preventive MedicineMeta-Analysis2023·24 citations

Cost-Effectiveness of Executive Health Screening Packages: A 3-Year Review

Dr. Haslina Bakar, Tan Wei Jian · Preventive Medicine Journal

Review of 1,850 executive screening participants. Downstream detection of stage-I cancer and pre-diabetes yielded RM 3.2M in avoided treatment costs over 3 years.

#screening#economics#prevention